Both CORE Clinical and CORE Biosciences have interest and expertise in learning more about the tear film, dry eye and related physiological processes.
CORE Clinical works in vivo to understand:
- dry eye disease and treatment,
- the ocular response to contact lens wear,
- tear film characteristics,
- meibomian gland dysfunction,
- tissue assessment.
CORE Biosciences works with:
- in vitro models
- live imaging of cell morphology
- inflammatory markers and other biomarker analysis
More about CORE’s work with dry eye and the tear film:
Kroeker D, van Doorn K, Walther H, Subbaraman L, Jones L. Development of a novel, objective metric to determine tear film stability. Invest Ophthalmol Vis Sci 2017;E-Abstract 3089.
Ng AY, Keech A, Jones L. Detection of tear film osmolarity changes after use of a hydroxypropyl guar-based lubricating eye drop. Invest Ophthalmol Vis Sci 2015;56: E-abstract 4429.
Ngo W, Srinivasan S, Houtman D, Jones L. The relief of dry eye signs and symptoms using a combination of lubricants, lid hygiene and ocular nutraceuticals. J Optom 2017;10(1): 26-33.
Ngo W, Caffery B, Srinivasan S, Jones L. Effect of lid debridement-scaling on dry eye signs and symptoms in Sjögren’s Syndrome. Invest Ophthalmol Vis Sci 2015;56: E-abstract 2487.