Tear film and dry eye

Both CORE Clinical and CORE BioSciences have interest and expertise in learning more about the tear film, dry eye and related physiological processes.

CORE Clinical works in vivo to understand:

  • dry eye disease and treatment,
  • the ocular response to contact lens wear,
  • tear film characteristics,
  • meibomian gland dysfunction,
  • tissue assessment.

CORE BioScience works with:

  • in vitro models
  • live imaging of cell morphology
  • inflammatory markers and other biomarker analysis

More about CORE’s work with dry eye and the tear film:

Kroeker D, van Doorn K, Walther H, Subbaraman L, Jones L. Development of a novel, objective metric to determine tear film stability. Invest Ophthalmol Vis Sci 2017;E-Abstract 3089.

Ng AY, Keech A, Jones L. Detection of tear film osmolarity changes after use of a hydroxypropyl guar-based lubricating eye drop. Invest Ophthalmol Vis Sci 2015;56: E-abstract 4429.

Ngo W, Srinivasan S, Houtman D, Jones L. The relief of dry eye signs and symptoms using a combination of lubricants, lid hygiene and ocular nutraceuticals. J Optom 2017;10(1): 26-33.

Ngo W, Caffery B, Srinivasan S, Jones L. Effect of lid debridement-scaling on dry eye signs and symptoms in Sjögren’s Syndrome. Invest Ophthalmol Vis Sci 2015;56: E-abstract 2487.