Development of in vitro models
Dry eye disease
Live imaging of cell morphology
Ocular response to contact lens wear
Tear film characterization (physical and chemical)
Tissue assessment: meibomian glands and lid wiper
Tear Film and Dry Eye
Refractive Error Correction and Control
Myopia prevalence
Myopia progression in children
Orthokeratology
Post-Lasik evaluations
Prevalence of uncorrected refractive error
Spectacle studies
Practitioner, Patient and Consumer Perspectives
Comfort with contact lens products
Compliance with recommended lens care hygiene and replacement schedule
Development of subjective tools
Focus groups and one-on-one interviews
Real-world responses to product performance
Web-based surveys
Ocular Surface Sensitivity and Symptoms
Comfort
Corneal and conjunctival sensitivity
Correlation between signs, symptoms and tear film deposition
Development of subjective rating scales
Microbiology and Toxicology
Bacterial binding to contact lenses
Biofilm formation on contact lenses and lens cases
Efficacy of biomaterials in blocking ultraviolet radiation
Ocular surface cell response to adverse conditions
Corneal and Conjunctival Physiology
Development of in vitro models
Dry eye disease
Live imaging of cell morphology
Ocular response to contact lens wear
Physical and chemical characterization of the tear film
Tissue assessment: meibomian glands and lid wiper
Contact Lens Care Products
Antimicrobial efficacy
Cleaning efficacy
Cytotoxicity
Efficacy of rewetting drops
Physical properties
Uptake/release of biocides
Contact Lens Materials
Adherence of cosmetics to lens materials
Characterization of the surface and bulk properties of contact lens materials
Clinical correlates of biomaterial properties
Distribution of tear film deposits within contact lens materials
Efficacy of ultraviolet ocular protection
Quantification and characterization of tear film deposits
Join Our Team of Research Participants
Study participants receive $20 per hour. Time commitment varies from study to study. All studies conducted by the CORE have received ethics clearance through the Office of Research Ethics at the University of Waterloo.
Biomaterial Engineering
Development of model conventional and silicone hydrogel lens materials
Engineering of contact lens materials for ocular drug delivery
Incorporation of novel substances to enhance properties of model lens materials