CORE’s multidisciplinary biosciences team works together to investigate fundamental research questions relating to the ocular surface and biomaterials, particularly contact lenses.
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Questions that arise during our clinical research can often be explored in vitro, and vice versa.
- Biomaterials (drug uptake and release, engineering, molecular imprinting)
- Cell analysis (phenotype, morphology, cytotoxicity, inflammatory markers)
- Contact lens materials (tear film deposits, lens surface and bulk characteristics, water content, metrology)
- DNA extraction
- Contact lens care systems (physical characteristics, cleaning and antimicrobial efficacy, cytotoxicity)
- Meibum analysis
- Microbiology (antimicrobial efficacy, bacterial adhesion and growth, biofilm evaluation, contamination, endotoxins, microbial identification, microbiome studies)
- Tear film analysis (cytokines, ferning, lipids, proteins, osmolality, neuropeptides)